BRAIN and NERVE Shinkei Kenkyu no Shinpo Volume 70, Issue 11 (November 2018)

Delusions in Dementia Yasuhiro Nagahama 1 1Kawasaki Memorial Hospital Keyword: アルツハイマー病 , レヴィ小体型認知症 , 被害妄想 , 前頭葉 , 社会脳 , Alzheimer disease , dementia with Lewy bodies , persecutory delusions , frontal cortex , social cognition pp.1139-1145
Published Date 2018/11/1
  • Abstract
  • Look Inside
  • Reference


Delusion is a common neuropsychiatric symptom in dementia, especially in Alzheimer disease and dementia with Lewy bodies. Persecutory delusions are the most common, and include delusions of theft, jealousy, and abundant. Patients with persecutory delusions have impairment of the psychological processes mediating the formation and maintenance of normal social beliefs. Several disordered psychological processes such as attentional bias, attributional bias, jumping-to-conclusions reasoning bias, and theory of mild deficit may contribute to the delusion formation. Cognitive processes involving information about self, others, and social interaction are required in social cognition. Damage of the neural circuitry involved in social cognition (“social brain”), such as the medial prefrontal cortex, may be a neuroanatomical basis for persecutory delusions in dementia.

Copyright © 2018, Igaku-Shoin Ltd. All rights reserved.


BRAIN and NERVE-神経研究の進歩
70巻11号 (2018年11月)
電子版ISSN 1344-8129 印刷版ISSN 1881-6096 医学書院