BRAIN and NERVE Shinkei Kenkyu no Shinpo Volume 68, Issue 2 (February 2016)
Japanese

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Abstract

Dementia with Lewy bodies (DLB) shows lesser memory impairment and more severe visuospatial disability than Alzheimer disease (AD). Although deficits in both consolidation and retrieval underlie the memory impairment, retrieval deficit is predominant in DLB. Visuospatial dysfunctions in DLB are related to the impairments in both ventral and dorsal streams of higher visual information processing, and lower visual processing in V1/V2 may also be impaired. Attention and executive functions are more widely disturbed in DLB than in AD. Imitation of finger gestures is impaired more frequently in DLB than in other mild dementia, and provides additional information for diagnosis of mild dementia, especially for DLB. Pareidolia, which lies between hallucination and visual misperception, is found frequently in DLB, but its mechanism is still under investigation.


Copyright © 2016, Igaku-Shoin Ltd. All rights reserved.

基本情報

18816096.68.2.jpg
BRAIN and NERVE-神経研究の進歩
68巻2号 (2016年2月)
電子版ISSN 1344-8129 印刷版ISSN 1881-6096 医学書院

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