Target Molecule for a Demyelinating Type of Guillain-Barré Syndrome, Acute Inflammatory Demyelinating Polyneuropathy Masahiro Mori 1 1Department of Neurology, Graduate School of Medicine, Chiba University Keyword: ギラン・バレー症候群 , 急性炎症性脱髄性多発ニューロパチー , 標的分子 , モエシン , サイトメガロウイルス , Guillain-Barré syndrome , acute inflammatory demyelinating polyneuropathy , target molecule , moesin , cytomegalovirus pp.1359-1369
Published Date 2015/11/1
DOI https://doi.org/10.11477/mf.1416200306
  • Abstract
  • Look Inside
  • Reference


Guillain-Barré syndrome is classified into demyelinating type, acute inflammatory demyelinating polyneuropathy (AIDP) and axonal form, acute axonal motor neuropathy (AMAN). It has been clearly established that the target molecule for the former is a ganglioside. In contrast, despite years of effort, the target molecule for the latter has not been identified. Recently, molecules around the nodes of Ranvier have entered the spotlight, and "moesin" was reported to be a target molecule for cytomegalovirus associated-AIDP.

Copyright © 2015, Igaku-Shoin Ltd. All rights reserved.


電子版ISSN 1344-8129 印刷版ISSN 1881-6096 医学書院