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Japanese

EVALUATION OF THE ALPHA SUBUNIT OF S100 PROTEIN IN SERA AS A TUMOR MARKER FOR RENAL CELL CARCINOMA Munehisa Takashi 1 , Yuanyuan Zhu 1 , Soichiro Hasegawa 1 , Koji Miyake 1 , Yasuharu Takagi 2 , Kanefusa Kato 3 1Department of Urology, Nagoya University School of Medicine 2Urology, Kakegawa General Hospital 3Biochemistry, Institute for Developmental Research, Aichi Prefectural Colony Keyword: 腎細胞癌 , 腫瘍マーカー pp.1055-1059
Published Date 1990/12/20
DOI https://doi.org/10.11477/mf.1413900214
  • Abstract
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To evaluate whether the alpha subunit of S100 protein (S100-α) in sera is a useful marker for renal cell carcinoma, we determined levels of serum S100-α in patients with renal cell carcinoma (n=100), other urogenital tumors (n=60), and benign urogenital diseases (n=25) with an enzyme immunoassay system. Serum S100-α levels were elevated (more than 500 pg/ml) in 29 of the 100 patients (29%) with renal cell carcinoma. With regard to the stage the positive rates were 20% in stage I , 18% in stage II, 31% in stage III, and 44% in stage IV.


Copyright © 1990, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1332 印刷版ISSN 0385-2393 医学書院

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