A case of renal angiomyolipoma accompanied with multifocal micronodular type 2 pneumocyte hyperplasia Shigenori Yonemura 1 , Kouji Katsuta 2 , Osamu Hataji 3 , Kiminobu Arima 4 , Masaki Sakurai 1 1Department of Urology, Matsusaka City Hospital 2Department of Pathology, Matsusaka City Hospital 3Department of Internal Medicine, Matsusaka City Hospital 4Department of Nephro-Urologic Surgery, Mie University Graduate School of Medicine Keyword: 腎血管筋脂肪腫 , 結節性硬化症 pp.969-973
Published Date 2012/11/20
DOI https://doi.org/10.11477/mf.1413102957
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A 52-year-old woman with a history of tuberous sclerosis complex was incidentally found to have right renal mass. Abdominal computed tomography(CT)showed renal mass with no fat component. Histological examination obtained by renal mass biopsy revealed leiomyosarcoma. Chest CT showed multiple micronodules. Radical nephrectomy was performed. Histological examination revealed the tumor composed of spindle cells arising from the renal capsule. She received adjuvant chemotherapy containing of cyclophosphamide, vincristine, adriamycin, dacarbazine. How ever no changes in the size and the number of lung metastasis were seen for 4 years. Video-assisted thoracoscopic surgery for lung nodules was done and histological examination revealed micronodular type 2 pneumocyte hyperplasia. To reevaluate the histological finding was leiomyosarcoma, we performed additional immunohistochemical examinations of renal tumor, and smooth muscle cells were positive for HMB-45. We finally obtained the diagnosis of angiomyolipoma arising from renal capsule associated with MMPH.

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