高カルシウム血症を伴う腎盂扁平上皮癌

A case of renal pelvic squamous cell carcinoma accompanied with hypercalcemia

症例は61歳女性，倦怠感・腹部腫瘤を主訴に来院し，精査加療目的に入院。入院時に炎症反応や血中SCC，血清カルシウムの高値を認めていたものの，悪性を確定できる所見はなかった。しかし，抗菌薬にて炎症が改善しないため左腎全摘術を施行せざるを得なかった。病理組織学的診断は扁平上皮癌であった。腎盂扁平上皮癌に合併する高カルシウム血症の報告例は非常に少なく，調べ得た限り本邦10例目であった。

A 61-years-old woman was admitted to our hospital with a chief complaint of general fatigue and abdominal mass. CT scan showed left hydronephrosis with staghorn calculus. But renal pelvic mass was not obviously. Laboratory data showed marked hypercalcemia and serum squamous cell carcinoma（SCC）. We performed left nephrectomy under the diagnosis of renal abscess. Pathological diagnosis was the renal pelvic squamous cell carcinoma. In this case hypercalcemia was regarded caused by HHM（humoral hypercalcemia of malignancy）. Only 10 cases of renal pelvic squamous cell carcinoma accompanied with hypercalcemia were reported in Japan.