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症例は70歳,男性。PSA 654ng/mlと高値を認め,また陰茎に複数の小腫瘤も認め受診した。前立腺針生検にてGleason score 4+4=8の前立腺癌を認めた。同時に陰茎腫瘍切除術を施行し,同様の前立腺癌細胞を認め,前立腺癌陰茎転移と診断した。画像検査では,肺,骨盤内リンパ節,全身骨にも転移を認め,現在ホルモン療法を行っているが,PSAも順調に低下し,陰茎腫瘤も消退している。
A 70-year-old man presented to our hospital in April 2007 with elevated serum prostate-specific antigen(PSA)and painful nodules on his penis. Digital rectal examination revealed a hard enlarged prostate. He underwent prostate needle biopsy and surgical removal of his penile nodules. Pathological examinations revealed prostate adenocarcinoma with penile metastases. The patient was finally diagnosed as prostate cancer stage D2(T3aN1M1c)with bone, lymph node, lung and penile metastases. He has shown successful recovery with significant improvement of serum PSA after MAB therapy.(Rinsho Hinyokika 62:251-253, 2008)
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