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IDIOPATHIC HYPOPARATHYROIDOSIS WITH REMARKABLE SKIN MANIFESTATION Kyoko HIRANO 1 1Department of Dermatology, Kyorin University pp.991-998
Published Date 1972/11/1
DOI https://doi.org/10.11477/mf.1412201063
  • Abstract
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 A 51-year-old man, who had had malaria in the past and had cataract, coxitis deformans and epilepsy was treated as epilepsy for about 7 years. Last spring, when the patient suffered from frequent attacks, he developed pruriginous, exfoliative dermatitis-like lesion over the entire body, except the face, and depilation of scalp and axillar hairs and roughness of the nails.

 Idiopathic parathyroid hypofunction was confirmed by the laboratory examinations.

 With the administration of vitamine D2 and gluconic acid calcium, the seizures disappeared on the next day and skin condition improved rapidly, leaving slight degree of pigmentation. Scalp and axillar hairs regenerated.

 Whereas dryness and roughness of the skin, depilation and change of the nail are the usual skin manifestations of the disease, the case developed such remarkable skin lesion is the first one in Japan. Only 3 cases of the disease are collected in the literature.

 Current concept upon the etiology of the disease is obscure, however, recent investigation favours the view of organ specific autoimmun disease.


Copyright © 1972, Igaku-Shoin Ltd. All rights reserved.

基本情報

電子版ISSN 1882-1324 印刷版ISSN 0021-4973 医学書院

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