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ASPERGILLOSIS CUTIS ACNEIFORMIS Tomotaka CHUJO 1 , Yoshiaki TSUJIGUCHI 1 , Reigo WADA 1 1Department of Dermatology, Nihon University School of Medicine pp.673-678
Published Date 1970/7/1
DOI https://doi.org/10.11477/mf.1412200682
  • Abstract
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A 41-year-old man showed the acneiform eruption in the indurated skin on the right scapular region after the operation of changing the mitral valve to a metalic one for the stenosis and incomplete closure of the mitral valve, It started after the postoperative administration of anti-biotics and adrenocortical hormone, and showed a remarkable improvement by a topical applica-tion of nystatin.

Histologic specimen showed folliculitis, with destruction of hair follicle and infiltration of his-tiocytes, plasma cells and lymphocytes around the polynuclear Leucocytes accumulation. Few foreign-body giant cells were observed. Keratotic cysts could be found, in which fungus elements were proved by PAS staining.

Aspergillus flavus was cultivated on Sabouraud's Glucose Agar from the pus and tissue.Intraperitoneal inoculation of this strain of the fungus introduced white nodules in the liver, kidney, and bladder with the histologic finding of which was an exudative inflammatory reaction containing the spore.

Sensitivities of this fungus to Amphotcricin B and Nystatin were 250 r/ml and 80 u/ml respec-tively.


Copyright © 1970, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1324 印刷版ISSN 0021-4973 医学書院

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