原発不明頸部リンパ節転移癌16例の臨床統計

Metastatic carcinomas of the neck of unknown primary

はじめに

　原発不明頸部リンパ節転移癌とは，病理学的に癌が証明された頸部リンパ節が存在し，種々の検索にもかかわらず原発巣が見出せない病態である^1,2）。従来は予後不良な疾患であったが，近年の集学的治療の発展により生存率は向上してきている。今回われわれは，当科を受診した原発不明頸部リンパ節転移癌症例の治療成績を報告する。

　We retrospectively analyzed 16 cases of metastatic carcinomas of the neck of unknown primary. The patients were 14 men and 2 women aged 51-75 years. The histopathological type was squamous cell carcinoma in 15 cases. Two and 14 patients were in stages Ⅲ and Ⅳ, respectively. Ten patients underwent neck dissection followed by chemoradiotherapy, and the remaining 6 patients received radical or palliative（chemo）radiotherapy. The overall 5-year crude/disease-specific survival rates were 48.1/57.9％. N3 lymph nodes, stages IVB/C and absence of neck dissection were negative prognostic factors. Early detection and effective treatment for advanced-stage patients are necessary to improve the prognosis of this disease.