診断に苦慮した鼻腔NK/T細胞リンパ腫の1例

Nasal NK/T-Cell Lymphoma

I．はじめに

　鼻腔NK/T細胞リンパ腫は，臨床的には顔面正中部に沿って進行する壊死性肉芽腫性病変を主体とする疾患で，病理組織学的に高度の壊死像と細胞浸潤のためしばしば確定診断がつきにくい特徴がある^1）。

　今回われわれは，確定診断がつくまでに他院での施行を含めて3回の生検を施行し，5クールのCHOP療法，放射線照射でCRとなった後に再発を認めた症例を経験したので，若干の考察を加えて報告する。

　A nasal NK/T-cell lymphoma in a 68-year-old man who complained of nasal obstruction from Dec. 2002 and left epistaxis from Jan. 2003 was reported. He was treated as common cold for 5months at a local ENT clinic. No clinical improvement was obtained,and he was referred to our hospital in May. Physical examinations disclosed a neoplasm located in the left lower turbinate. And its surface was rough,eroded and hemorrhagic. The lower turbinate resection was done under general anesthesia. After the operation,he received chemotherapy and radiotherapy. The patient was followed and alive at the time of this report.