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Primary Jejunal NK/T Cell Lymphoma, Report of a Case Yuji Okada 1 , Tomoyuki Ohta 1 , Momotaro Muto 1 , Masayuki Beppu 1 , Hiroshi Tomioka 1 , Hisato Amizuka 1 , Ken Hasegawa 2 , Eiji Inagi 2 , Sanshiro Kigawa 2 , Kazuo Nagashima 3 , Shinya Tanaka 4 , Takashi Yao 5 1Department of Gastroenterology, Sapporo Higashi-Tokushukai Hospital 2Department of Surgery, Sapporo Higashi-Tokushukai Hospital 3Department of Pathology, Sapporo Higashi-Tokushukai Hospital 4Department of Molecular and Cellular Pathology, Hokkaido University School of Medicine 5Department of Anatomic Pathology, Graduate School of Medical Science, Kyushu University Keyword: 小腸悪性リンパ腫 , NK/T細胞リンパ腫 pp.386-392
Published Date 2006/3/25
DOI https://doi.org/10.11477/mf.1403100295
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 An asymptomatic 78-year-old woman was admitted to hospital in Dec., 2003, for investigation relating to her anemia. Laboratory data showed a high level of sIL-2 receptor (925U/ml). Small bowel radiography and push enteroscopy revealed a deep irregular ulceration 8cm in diameter but without intestinal stenosis at the upper jejunum, and suggested an aneurysmal type of intestinal malignant lymphoma, which was pathologically verified by endoscopic biopsy. Systemic CT scan showed no lymphadenopathy and no hepatic or pulmonary metastasis. The patient had initially undergone surgery for progressive anemia. During laparotomy, the tumor was located in the jejunum and had directly invaded the neighboring ileum. Immunohistochemical studies of the resected tumor showed that tumor cells were positive for CD3 and CD56, but negative for CD20 and CD79α. On the basis of these findings, this case was diagnosed as NK/T cell lymphoma of the small intestine. The patient died about four months after surgery because of this progressive disease, consistent with the poor prognosis of NK/T cell lymphoma.


Copyright © 2006, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1219 印刷版ISSN 0536-2180 医学書院

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