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Epidermal growth factor in aqueous humor of cataractous eyes Miki Hongo 1 , Yasuyuki Tanaka 2 , Shigeru Kinosita 2 , Nozomi Yamaguchi 3 , Jiro Imanishi 4 1Dept of Ophthalmol, Ayabe Municipal Hosp 2Dept of Ophthalmol, Kyoto Prefectural Univ of Med 3Research Ins for Neurological Diseases and Geriatrics, Kyoto Prefectural Univ of Med 4Dept of Microbiology, Kyoto Prefectural Univ of Med pp.1053-1056
Published Date 1993/5/15
DOI https://doi.org/10.11477/mf.1410908642
  • Abstract
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We quantitated the human epidermal growthfactor (h-EGF) in the aqueous humor in 16 other-wise uncomplicated cataractous human eyes. Theage averaged 72.5 years. Enzyme immunoassaymethod was used in quantitation of h-EGF. Recur-sive analysis of absorption at 490 nm using stan-dard h-EGF, we observed a proportionate relation-ship between absorbance and the concentration ofh-EGF over a range from 78.1 to 625 pg/ml. Levelsof h-EGF from 165 to 1078 pg/ml, average 391.8pg/ml, were observed in 12 eyes, 75%. The findingssuggest that h-EGF may also be present in theaqueous humor of normal human eyes.


Copyright © 1993, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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