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Elevation of intraocular pressure induced by mydriatics in open angle glaucoma Ikuko Ichioka 1 , Takashi Ichioka 1 , Hiroshi Ichioka 1 1Ichioka Eye Clinic pp.1139-1143
Published Date 2000/6/15
DOI https://doi.org/10.11477/mf.1410906896
  • Abstract
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We investigated the changes in intraocular pressure (IOP) following instillation of MydrinTM which contains 0.5% tropicamide and 5% phenilephrine. The tested eyes comprised open-angle glaucoma 40 eyes, capsular glucoma 16 eyes, normaltension glaucoma 35 eyes and 434 eyes without glaucoma. One hour after two instillations of mydriatics with an interval of 5 minutes, the TOP rose by an average of 2.6±2.7 mmHg in POAG, 2.7±2.0 mmHg in capsular glaucoma, and 0.1±1.5 mmHg in eyes without glaucoma. The IOP elevation was significant in open-angle and capsular glaucoma (P<0.0001 each, student t-test). Four glaucoma eyes (35%) and 6 capsular glaucoma eyes showed IOP elevation by 4 mmHg or greater. The findings show that due precaution is necessary in attempting mydriasis in open-angle or capsular glaucoma eyes.


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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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