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(P−2-141) 1998年までの約14年間に眼底検査を行った低出生体重児852例での未熟児網膜症を検討した。出生体重は424gから2,492g,平均1,601gであり,在胎週数は24週から38週,平均31.8週であった。未熟児網膜症は852例中262例(30.8%)にあり,うち71例(83%)が治療を必要とした。治療を行ったのは138例中14例(10.1%)(1985〜87年),281例中28例(10.0%)(1988〜91年),266例中22例(8.3%)(1992〜95年),167例中7例(4.2%)(1996〜98年)であった。治療の結果は71例中69例(97%)で良好であった。1眼が瘢痕期2度強度,1眼が瘢痕期5度を残した0以上の結果は在胎週数,そして出生体重が少ないほど発症率が高く重症化する傾向にあり,29週以下の在胎週数と1,500g以下の出生体重のときに未熟児網膜症が急増することを示している。
We reviewed 852 low-birthweight infants seen during the 14 years through 1998. Their birthweight ranged from 424 to 2,492 g, average 1,601 g. The gestational age ranged from 24 to 38 weeks, average 31.8 weeks. Retinopathy of prematurity (ROP) was detected in 262 out of 852 cases (30.8%) , of which 71 cases (8.3%) required treatment. Specifically, treatment was performed in 14 out of 138 cases (10.1%) in 1985-87, in 28 out of 281 cases (10.0%) in 1988-91, in 22 out of 266 cases (8.3%) in 1992-95, and in 7 out of 167 cases (4.2%) in 1996-98. The outcome of treatment was favorable in 69 of the 71 cases (97%). One eye resulted in severe grade II cicatricial phase and another in grade V. In any groups, particularly in those with gestational age of shorter than 29 weeks and birth weight of less than 1,500g were higher incidence of ROP and became severe.
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