Infiltrative optic neuropathy in a case of malignant lymphoma during remission Naoki Iino 1 , Yoshimi Kubota 1 , Hiroshi Watanabe 1 , Tetsuo Tochikubo 1 1Dept of 1st Ophthalmol, Toho Univ Sch of Med pp.1051-1054
Published Date 1998/6/15
DOI https://doi.org/10.11477/mf.1410905916
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A 70-year-old male developed sudden visual impairment in his right eye. He had been diagnosed as non-Hodgkin lymphoma 3 years 8 months before. He was in a state of complete remission following systemic corticosteroid and radiation. The corrected visual acuity in the affected eye was 0.08. The optic disc was hyperemic and was swollen. We diagnosed the condition as infiltrative optic neuropathy. Systemic corticosteroid and radiation to the optic nerve resulted in improvement in visual acuity to 0.8 4 weeks later. The visual acuity decreased to 0.01 3 weeks later associated with recurrence of disc swelling. The final visual acuity remained at 0.1 in spite of radiation treatment. This case illustrates that infilatrative optic neuropathy may occur during the remission of malignant lymphoma with a tendency to recurrence.

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