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Chemotherapy was effective in a case with optic nerve involvement by malignant lymphoma Machiko Yano 1 , Noriko Hashiba 1 , Noboru Horikoshi 2 , Takumi Akashi 3 , Takayuki Akaboshi 4 1Dept of Ophthalmol Cancer Institute Hosp 2Dept of Chemotherapy Cancer Institute Hosp 3Dept of Pathol, Cancer Institute Hosp 4Dept of Ophthalmol, Tokyo Univ pp.1673-1676
Published Date 1989/10/15
DOI https://doi.org/10.11477/mf.1410211019
  • Abstract
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A 61-year-old male presented with bilateral blurring of vision. He had been diagnosed as B-cell type malignant lymphoma 2 years before. He had gone through several courses of systemic chemo-therapy because of widespread lymph node involve-ments and multiple tumors in the alimentary tract.He manifested, ophthalmoscopically, findings simulating papillitis. The visual field was irregular-ly affected bilaterally. These findings suggested bilateral involvement of the optic nerve by malig-nant lymphoma. The ocular lesions prompted re-sponded to systemic chemotherapy. He died of respiratory failure 5 months after first visiting us.Postmortem studies revealed extension of malig-nant lymphoma to bilateral optic nerves in addition to lymph nodes, liver, spleen, alimentary tract, dura mater and the subarachnoid space.


Copyright © 1989, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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