Posttraumatic corneal perforation in a case of progressive systemic sclerosis Tomo Suzuki 1 , Chie Sotozono 1 , Hisano Soma 2 , Shigeru Kinoshita 1 1Dept of Ophthalmol, Kyoto Prefec Univ of Med 2Dept of Ophthalmol, Uji Tokushukai Hosp pp.903-906
Published Date 1998/5/15
DOI https://doi.org/10.11477/mf.1410905885
  • Abstract
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A 70-year-old woman developed a corneal ulcer after the tip of eyedrop dispenser came into contact with the right eye. She had a 5-year history of progressive systemic sclerosis. The cornea perforated 7 days after the accident. The perforation was located in the center of corneal ulcer of about 2mm×4mm in size. Wearing of therapeutic soft contact lens, topical antibiotics, and topical and systemic corticosteroid resulted in regeneration of corneal stroma and closure of perforated wound one week later. It appeared that the corneal perforation was caused by excessive production of inflam-matory mediators during corneal epithelialization.

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