Japanese

Abnormalities of retinal pigment epithelium in five cases of familial adenomatous polyposis Sachiko Fukuoka 1 , Yuka Kobayashi 1 , Shigeo Miyazaki 1 , Akio Tabuchi 1 , Sachio Kawashima 2 , Mitsuo Iida 3 1Dept of Ophthalmol, Kawasaki Med Sch 2Kawashima Eye Clinic 3Div of Gastroenterol, Dept of Med, Kawasaki Med Sch pp.871-874
Published Date 1998/5/15
DOI https://doi.org/10.11477/mf.1410905877
  • Abstract
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We observed abnormalities of retinal pigment epithelium (RPE) in five cases of familial adenomatous polyposis. All the cases showed uneven distribution of RPE pigment in the posterior and midperipheral fundus. Three cases showed hypertrophy of RPE. The hypertrophic lesions appeared as low and high signal areas by argon green (514 nm) when seen by a scanning laser ophthalmoscope (SLO) . They appeared as high signal areas by infrared (780 nm) by SLO. Fluorescein and indocyanine green angiography showed occlusion of the choriocapillaris in some lesions. Uneven pigment distribution in the RPE was detected by infrared. These fundus findings seem to be new characteristic features of familial adenomatous polyposis.


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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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