Three cases of acquired ocular toxoplasmosis Tohru Fukai 1 , Hiroshi Goto 1 , Toshihiro Ichikawa 1 , Ryuji Muramatsu 1 , Masahiko Usui 1 , Keiji Nerome 2 1Dept of Ophthalmol, Tokyo Med Coll 2Dept of Ophthalmol, Nakagami Hosp pp.1537-1542
Published Date 1996/8/15
DOI https://doi.org/10.11477/mf.1410905031
  • Abstract
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Ocular toxoplamosis usually develops by reactivation of congenitally dormant infection.Acquired ocular toxoplasmosis is rather infrequent in Japan. We observed atypical acquired ocular toxoplas-mosis in three females aged 42, 51 and 54 years each. One case had been treated for toxoplasmic uveitis.When first seen by us, her right eye showed intense vitreous opacity and proliferative preretinal membrane.The aspirated aqueous showed toxoplasma coefficient of Goldmann-Witmer of 33×. Vitrectomy aftersystemic acetylspiramycin resulted in improvement in visual acuity. The other two cases showed multipleyellowish-white lesions in the deep retinal layer with minimum vitreous opacity. One case showed elevatedserum antibody to toxoplasma. Indocyanine green angiography showed hypofluorescence in affected retinalareas throughout the angiographic phases. Systemic acetylspiramycin induced resolution of the exudativelesions.

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