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Treatment of chronic dacryocystitis due to methicillin-resistant Staphylococcus aureus based on pharmacokinetics Hiromi Jinbayashi 1 , Akihiro Ohira 1 , Tsugio Amemiya 1 , Kenji Matsuyama 2 1Dept of Ophthalmol, Nagasaki Univ Sch of Med 2Dept of Hosp Pharmacy, Nagasaki Univ Hosp pp.779-781
Published Date 1996/5/15
DOI https://doi.org/10.11477/mf.1410904864
  • Abstract
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A 63-year-old female had been suffering from chronic dacryocystitis for the past 15 years. Methicillin-resistant Staphylococcus aureus (MRSA) was isolated during a recent acute exacerbation. She was treated daily by intravenous infusion of minocycline and vancomycin. The concentration of vancomycin in the circulating blood was monitored before infusion, 2 hours after end of infusion and just before the next infusion. This procedure enabled determination of minimum effective dosis avoiding renal impairment. Acute inflammation subsided after 10 days of treatment.


Copyright © 1996, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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