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Causative factors of interferon retinopathy Keiji Sugasawa 1 , Misako Hagiwara 1 , Toyokazu Okami 1 , Kanji Takahashi 1 , Masanobu Uyama 1 , Toshiya Hirota 2 , Hiroyasu Okuno 2 1Dept of Ophthalmol, Kansai Med Univ 2Dept of Intl Med, 3rd Division, Kannsai Med Univ pp.385-389
Published Date 1996/3/15
DOI https://doi.org/10.11477/mf.1410904777
  • Abstract
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We evaluated the incidence of retinopathy in 38 patients who were treated by systemic interferon preparations. Interferon-α was given to 26 patients with chronic hepatitis C. Interferonβ was given to 12 patients with age-related exudative macular degeneration. The incidence of retinopathy was 47% in the former group and 42% in the latter. The difference was not significant. There were no differences in hematological findings between those who developed retinopathy and those who did not in either group. These findings show that interferon retinopathy may be caused by direct effects of interferon on the retinal microcirculatory system.


Copyright © 1996, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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