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Topical vancomycin for ocular infection by methicillin-resistant Staphylococcus aureus Yasunori Tadokoro 1 , Hiroshi Ohtsuki 2 , Masaki Okano 2 , Sei Watanabe 3 1Dept of Ophthalmol, Mihara Red-Cross Hosp 2Dept of Ophthalmol, Okayama Univ Sch of Med 3Dept of Ophthalmol, Ritsurin Hosp pp.521-525
Published Date 1995/3/15
DOI https://doi.org/10.11477/mf.1410904229
  • Abstract
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An 81-year-old woman presented chronic dacryocystitis in her right eye. Initial treatment with topical ofloxacin solution was unsatisfactory. Culture of purulent discharge from the affected lacrimal sac showed methicillin-resistant Staphylococcus aureus, MRSA, which was also resistant to commercially available topical antibiotics. As she declined surgical intervention, we prepared vancomycin hydrochloride ophthalmic solution, 50 mg/ml, using phosphate-buffered artificial tears as vehicle. Clinical and bacteriologi-cal cure resulted from topical instillation 4 times daily for 2 weeks.


Copyright © 1995, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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