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Corneal flattening in a case after cicatricial cure of acanthamoeba keratitis Maki Sekine 1 , Kimiko Takada 2 , Tomo Kimura 2 , Kazunori Miyata 2 , Makoto Araie 2 , Tadahiko Tsuru 3 , Takuro Endo 4 1Dept of Ophthalmol, Tokyo Univ Sch of Med 2Dept of Ophthalmol, Tokyo Univ Branch Hosp 3Sec of Corneal Transplantation, Univ of Tokyo Hosp 4Dept of Parasitol, National Inst of Health pp.1505-1508
Published Date 1994/8/15
DOI https://doi.org/10.11477/mf.1410903964
  • Abstract
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A 25-year-old male presented with geographic corneal ulcer in the right eye of presumably of 3 months' duration. He had been wearing soft contact lens for the past 6 years. The visual acuity was reduced to hand movement. Acanthamoeba cysts were present in the cultured corneal scrapings. Mitochondrial DNA analysis showed Moak strain Acanthamoeba. The condition responded favorably to topical and systemic fluconazole. Due to scarring, the cornea became highly flattened causing irregular astigmatism. Corrected visual acuity was 0.2 by spectacles. Hard contact lens improved the visual acuity to 0.6.


Copyright © 1994, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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