Surgical reconstruction of filtering bleb using mitomycin C Yukiko Hongo 1 , Takeshi Hara 1 , Shiroaki Shirato 1 1Dept of Ophthalmol, Facul of Med, Univ of Tokyo pp.147-150
Published Date 1994/2/15
DOI https://doi.org/10.11477/mf.1410903617
  • Abstract
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We performed surgical repair of filtering bleb with subconjunctival mitomycin C in 25 glaucoma eyes after failure of previous trabeclectomy with subconjunctival 5-fluorouracil. Preoperative intraocular pressure (IOP) under maximum tolerable medication ranged 20 to 35mmHg, mean 23.8mmHg. Follow-up period ranged 5 to 12 months, average 7.6 months. After surgery, the IOP was controlled below 20mmHg without medication in 18 eyes, 76%. The IOP in these eyes averaged 11.6±4.4mmHg. Additional topical medications were necessary to control the IOP in 5 of the remaining 7 eyes. The success probability assessed by life-table method was 88%, 72% and 72% at 1,6, and 12 months respectively. Postoperative complications included corneal epithelial defect 4%, conjunctival wound leak 4% and shallow or flat anterior chamber with choroidal detachment 12%. The finding suggest the usefulness of reconstruction of the filtering bleb with subconjunctival mitomycin C in cases of failed bleb.

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