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過去7年間に,名古屋市立大学病院眼科でサルコイドーシス(以下,サ症)を疑った58例(Ⅰ群),同院他科でサ症と診断され眼科を受診した55例(Ⅱ群)の初診時以降の眼病変の経過,治療および視力予後などを,6か月以上経過観察できた症例について検討した。Ⅰ群で25例,Ⅱ群で13例に新たな眼病変が出現した。出現した病変数は1個が多く,時期は80%以上が初診時から1年以内であり,種類は網膜血管周囲炎が多くみられた。Ⅰ群は眼科的に重篤であり,多数の症例でステロイド剤の局所注射や内服治療を必要とし,眼合併症,視力予後の不良例も多かった。初診時から最低1年間は厳重な眼科的管理が必要である。
We reviewed 58 cases of presumed monosympto-matic ocular sarcoidosis (group 1) and 55 cases of sarcoidosis with ocular and systemic involvements (group 2) during the foregoing 7 years. During the follow-up period, 25 cases in group 1 and 13 cases in group 2 manifested other typical signs of sar-coidosis which were absent initially. Retinal periph-lebitis was the most frequent one. These signs became manifest within one year in over 80% of the cases. Cases in group 1 tended to show severer ocular manifestations than in group 2, requiring topical and systemic corticosteroid therapy. Secon-dary glaucoma, complicated cataract and cystoid macular edema were also more frequent in the former. We advocate close follow-up of cases of sarcoidosis for at least one year after detection.
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