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Two cases of acute inner retinitis responded to treatment with antibiotics Akane Sobue 1 , Chiharu Iwahashi 2 , Yuki Hamano 1 , Yuka Umemoto 1 , Mami Haruta 1 , Takamasa Minami 1 , Hisashi Mashimo 1 , Nobuyuki Ohguro 1 1Department of Ophthalmology, Japan Community Health Care Organizaton Osaka Hospital 2Department of Ophthalmology, Kindai University Hospital pp.976-982
Published Date 2022/7/15
DOI https://doi.org/10.11477/mf.1410214448
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Abstract Purpose:We report two cases of acute inner retinitis that responded to treatment with antibiotics.

Cases:Case 1 is a 79-year-old woman presented with floater in her right eye. Slit-lamp examination showed anterior chamber inflammation in her right eye. The patient's best corrected visual acuity(BCVA)was 0.6 in the right eye. Fundus examination revealed diffuse vitreous opacity, retinal white lesions, and retinal hemorrhage. Optical coherence tomography(OCT)passing through the white lesion revealed a focal area of inner retinal thickening with hyperreflectivity. She was treated with oral minocycline(200 mg/day)for one month. The retinal lesions disappeared and her BCVA improved to 0.9.

Case 2 is a 60-year-old man presented with persistent intraocular inflammation that did not respond to steroid eye drops. His BCVA was 1.2 in the right eye and 0.8 in the left eye. Slit-lamp examination showed anterior chamber inflammation. Fundus examination showed retinal white lesions and branch retinal artery occlusion in both eyes. Fluorescein angiography showed retinal vasculitis. Similar to case 1, OCT showed an inner retinal layer hyperreflectivity consistent with the elevated retinal lesion in the left eye. He was treated with oral minocycline(200 mg/day), clarithromycin(400 mg/day)and subconjunctival injection of dexamethasone. After 2.5 months of medication, the inflammation disappeared and his BCVA improved to 1.2 in both eyes.

Conclusion:Antibiotic therapy may be successful in uveitis with white lesions in the inner retina.


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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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