Japanese

Outcome of percutaneous supratarsal injection of triamcinolone acetonide for vernal keratoconjunctivitis Hiroshi Fujita 1 , Yusuke Saeki 1 , Kazuhiro Harada 1 , Eiichi Uchio 1 1Department of Ophthalmology, Fukuoka University School of Medicine pp.1265-1272
Published Date 2020/10/15
DOI https://doi.org/10.11477/mf.1410213706
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Abstract Purpose:Vernal keratoconjunctivitis(VKC)often has its onset in childhood with a long-term treatment. Intraocular pressure(IOP)elevation due to corticosteroid treatment is a great concern as complication. We report subcutaneous supratarsal injection of triamcinolone acetonide(TA)as an alternative treatment for corticosteroid eye drops.

Cases and methods:Forty-one patients, 64 eyes, treated by subcutaneous supratarsal injection of TA at Fukuoka University Hospital in the decade from January 2009 to December 2018 were evaluated. The mean observation period was 35.7±32.5 months(0〜119 months). Patients' gender, age, seasonality, number of injection, age at first injection, interval between injections, eye drops before and after first injection and complications were analyzed by medical records retrospectively.

Results:Thirty-five patients were male and 6 were female, mean patient age was 11.4±6.18(range;4〜32 years)years. Total number of TA injection was 139, of these, 23 injections were done(16.5%)in July, 21 were done(15.1%)in March. Mean cumulative injection was 3.39±3.40(range;1〜13)for each eye. Eighteen patients needed multiple TA injections. Of these patients, 14 were male and 4 were female, mean age was 9.17±3.99(range;4〜19 years)years. Mean interval between injections was 11.0±6.07(range;1〜35 months)months. As complications, IOP elevation occurred in 3 patients(1 male, 2 females), hordeolum in 1 patient and extended lashes in 1 patient.

Conclusions:IOP elevation was very rare in cases treated with subcutaneous supratarsal injection of TA for refractory VKC compared to subconjunctival TA injection or systemic corticosteroid. It is suggested that this way of TA injection is a safe treatment, because its technique is easy and its interval between injections was long.


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