硝子体混濁と緑内障を伴った全身性アミロイドーシスの1例

A case of systemic amyloidosis with vitreous opac-ity and secondary glaucoma

　全身性アミロイドーシスに硝子体混濁，緑内障を合併した69歳男子を経験し，pars plana　vitrectomyにより視力の改善を得た。前眼部炎症所見を伴わない硝子体混濁に関しては，重要な鑑別疾患のひとつであると考えられた。

A 69-year-old man presented with progressive visual disturbance in both eyes of 8 years' duration. We observed, bilaterally, vitreous opacity, secon-dary glaucoma and pseudoexfoliation-like mate-rial on the anterior lens surface of the right eye. The visual acuity in the left eye improved afterpars plana vitrectomy. The surgically obtained vitreous specimen showed amyloid deposit by Congo-red staining and by electron microscopy. He was diagnosed as systemic amyloidosis by mucosal biopsy of the duodenum and the rectus. Ocular amyloidosis is to be suspected in a case of vitreous opacity without signs of iritis, even when systemic amyloidosis is uncertain.