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Japanese

Diabetic retinopathy during pregnancy in non-insulin dependent diabetics. Hiroshi Kidoguchi 1 , Ikuko Ohi 1 , Sadao Hori 1 , Akemi Shimizu 2 , Yasue Ohmori 2 , Yukimasa Hirata 2 1Dept of Diabeto-Ophthalmol, Diabetes Cent, Tokyo Women's Med Coll. 2Dept of Int Med, Diabetes Cent, Tokyo Women's Med Coll. pp.561-564
Published Date 1989/4/15
DOI https://doi.org/10.11477/mf.1410210722
  • Abstract
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We evaluated the course of diabetic retinopathy during 179 pregnancies in 152 females with non -insulin dependent diabetes mellitus. One preg-nancy was counted as one case, when a patient underwent more than pregnancies.

No detectable retinopathy was present in 132/179 cases (74%) when first seen after onset of preg-nancy. In these 132 cases, background retinopathy developed in 28 cases (21%). Retinopathy was con-sistently absent in the other 104 cases (79%). Retinopathy was already present in 47 cases(26%) when first seen after pregnancy. The state of retinopathy remained stationary in 29 cases (62%) and progressed in 18 (38%) during the course of pregnancy. We observed higher rate of exacerba-tion in cases with initial retinopathy with grading of All or more in Fukuda's classification.

Nine cases manifested preproliferative or proliferative retinopathy during pregnancy. Photocoagulation was followed by improvement in retinopathy in 5 and by further exacerbation in 2. We identified preexisting retinopathy, longer dura-tion of diabetes and poor glycemic control before onset of pregnancy as risk factors for exacerbation of retinopathy during pregnancy.


Copyright © 1989, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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