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Japanese

Two-step therapy for diabetic macular edema Yoshiyuki Koseki 1 , Shigehiko Kitano 1 , Sadao Hori 1 , Hiroshi Kidoguchi 1 , Takayuki Akahoshi 1 , Chiaki Nonaka 1 , Chikako Sutou 1 1Dept of Ophthalmol, Diabetic Center, Tokyo Women's Med Coll pp.1449-1451
Published Date 1991/8/15
DOI https://doi.org/10.11477/mf.1410900798
  • Abstract
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We treated 14 eyes, 12 patients, who manifested diffuse macular edema as complication of diabetic retinopathy. All the patients were under insulin therapy. As the first step of treatment, patients were given peroral prednisolone at the initial daily dosis of 30 mg. After improvement of funduscopic findings or visual acuity, we applied photocoagula-tion using dye laser either as focal or grid coagula-tion. At the end of averaged of 3.5 months aftercessation of prednisolone, visual acuity improved by 2 lines or more in 8 eyes, 57%, remained un-changed in 5 eyes, 36%, and deteriorated in 1 eye, 7%. The funduscopic feature of retinopathy ag-gravated in 2 eyes, apparently due to systemic corticosteroid.

As photocoagulation alone does not induce visual improvement in the presence of diabetic macular edema, the present two-step therapy promises to be of value in this clinical situation.


Copyright © 1991, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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