Sjögren症候群にみられた広範な網膜血管閉塞

Extensive capillary nonperfusion in the retina in a case of Sjögren's syndrome

　Sjögren症候群患者で，両眼にrubeosisiridisと著明な網膜血管障害を合併した1症例を報告する．

　64歳の女性患者は，両眼の瞳孔領近くに，rubeosisが生じ，螢光眼底造影では広範な網膜毛細血管網の閉塞，細動静脈の変形・血管透過性亢進，新生血管を認めた．Schirmer test,Rose-Ben-gal test,lip-biopsy，および唾液腺管造影からSjögren症候群と診断した．血清の免疫学的検査から，この症例はSjögren症候群と全身性エリテマトーデスとの中間型であると想定できた．

A 64-year-old female presented with rubeosis in both eyes. Fluorescein fundus angiography revealed extensive capillary nonperfusion, hyperper-meability of vessels and neovascularization. She was diagnosed as Sjögren's syndrome on account of positive Schirmer test, rose-bengal staining of con-sialography. Immunological studies suggested an intermediate type between Sjögren syndrome and systemic lupus erythematosus. The deficient autoimmune system was apparently causatively related with the observed retinal vascular abnor-malities.