Japanese

Cellular components of epiretinal membranes Miyo Matsumura 1 , Morio Okada 1 , Ryoji Yamakawa 1 , Nagahisa Yoshimura 1 , Hiroyasu Shirakawa 1 , Nobuchika Ogino 1 1Dept. of Ophthalmol, Fac of Med, Kyoto Univ pp.715-720
Published Date 1986/7/15
DOI https://doi.org/10.11477/mf.1410209773
  • Abstract
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We tried to histologically identify the cellular compo-nents of epiretinal membranes. The tissue specimens were obtained during vitrectomy in 45 cases including proliferative vitreoretinopathy (PVR), macular puckerfollowing retinal detachment surgery, premacular mem-brane with or without macular hole formation, diabetic retinopathy and others. Besides direct histological observation, tissue culture technique was applied to increase the amount of tissue specimen and to facilitate the identification of the nature of cellular components. This technique succeeded in 67% of cases with PVR.

The retinal pigment epithelial cells were the chief component of the epiretinal membrane in PVR. The cell types were variable in macular pucker. The macular epiretinal membranes with or without macular hole were characterized by their striking paucity in cellular components.

The present findings indicate that the cellular compo-nents of epiretinal membranes are highly variable according to the pathogenetic features. Tissue culture promises to be a useful adjunct in identifying the nature of surgically obtained tissue specimens.

Rinsho Ganka (Jpn J Clin Ophthalmol) 40(7) : 715-720, 1986


Copyright © 1986, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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