Opportunistic pathogenとしてのブドウ糖非発酵グラム陰性桿菌による眼感染症

Nonfermentative gram-negative bacilli as opportunistic pathogens in ocular infection

　ブドウ糖非発酵グラム陰性桿菌，P．　cepacia 10症例ならびにP．maltophilia 1症例の臨床的検討を行った。なお，P．　cepacia家兎眼接種実験で角膜炎の発症がみとめられた。

　本菌群は日常生活環境に広く常在して，二次的に眼感染症の原因菌となりうるもので，常用抗生剤，消毒薬に抵抗性の多いことから，院内感染，治療にあたっては十分に注意すべきこと，ならびに今後の臨床的検討が必要であることを述べた。

We observed 10 cases of corneal infection with purulent iridocyclitis due to Pseudomonas cepacia and a case of corneal ulcer due to Ps.maltophilia. Prior to corneal infection, 4 patients had suffered from ocular injurty and had been treated by anti-microbial agents including cephalosporins or ami-noglycosides. The causative organisms were isolated from corneal abrasion, aqueous humor and/or con-junctiva.

Strains of Ps.cepacia were almost consistently resistant to streptomycin, gentamicin, ampicillin, carbenicillin, cephaloridine and colistin.