放射線網膜症の臨床について

Clinical Features of Radiation Retinopathy

緒　言

　悪性腫瘍の治療には，手術，化学療法とともに放射線療法が行なわれ，眼近傍の照射の機会も多くなつて来た。原病の治療成績が向上した一方では，放射線眼障害も多く見られるようになり，最近では，網膜の障害に関する報告も増えてきた。著者らは，病院の性格上かなり多くの臨床的放射線網膜症に遭遇したのでここに報告する。

This paper describes the clinical features of 25 cases with radiation retinopathy. The reti-nopathy was induced following therapeutic irr-adiation of paraorbital malignancies with me-gavoltage Linac X-ray of 3,000 rads or more. Retinal vessels, particularly proximal portion of retinal arteries, seemed to be the primary site of damage due to radiation. According to the type of lesion and dosage, fundus features simulated papillitis, retinal angiosclerosis, or hard exudates due to capillary obliteration.Acute obstruction of central retinal artery and ischemic optic neuropathy could result follow-ing heavy irradiation of over 5,000 rads.