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Japanese

Studies on ophthalmic use of Taocin Masakiti Mikuni 1 , Masao Oishi 1 , Mikito Tanaka 1 , Kazuo Ishida 1 , Susumu Ono 1 1Dept. of Ophth.., Niigata Univ. School of Medicine. pp.747-753
Published Date 1961/6/15
DOI https://doi.org/10.11477/mf.1410207263
  • Abstract
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The results of some experiments for ophthalmic use of Triacetyloleandomycin (trade name "Taocin") were summerized as follows.

1) Serum levels by oral administration of 500mg Taocin in a single dose attained to the highest after 3 hours and maintained relatively higher serum levels still after 6 hours.

Compared with the similar dose of Oleandomycin, Taocin was found to be more later absorbed, while it produced consistently higher levels.

2) The application of 500mg Taocin in a single dose gave a penetration of 1.36 mcg /cc of oleandomycin into the aqueous of the human eye, the Blood-aqueous ratio being 46.8%.


Copyright © 1961, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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