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緒言
鉄片が眼内に残存すると眼内組織の障害が生じ,臨床的に鉄錆症が発現するが,その障害は眼内に平等に起こるのではなく,部位的に黄斑部が限局性変化を受けやすいことをHaabがはじめて記載して以来,内外ともに多くの報告がなされてきた。
最近では,牧内氏がサルの硝子体内に鉄片を挿入して実験を行ない,初期のおもな組織的変化はHenle線維層の浮腫,色素上皮細胞の変性,脈絡膜後極部の滲出液貯溜であり,従来の鉄錆症臨床報告例にみられるごとく,黄斑部が限局性に侵されるのを確認した。
Intraocular siderosis was experimentally pro-duced in 4 monkey eyes by inserting a small iron fragment into the vitreous and was follow-ed up by ophthalmoscopy and fluorescein angiography.
Both the ophthalmoscopic and fluorographic findings in normal monkey eyes were essential-ly similar to those in humans.
The onset of ocular siderosis was characte-rized by hyperemia of the optic disc, dilatation of retinal vessels and the retinal edema involv-ing the macular region. With the progression of ocular siderosis, the retinal vessels showed remarkable constriction and further increase of the macular edema.
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