黄色鉛筆による眼瞼肉芽腫とその実験的研究

A Case of the Lid Glanuloma Induced by a Yellow Pencil and Its Experimental Studies

緒言

　色鉛筆による眼障害に関しては，すでに古くから紫色鉛筆について詳細な報告があるが^1）〜12），黄色鉛筆による眼障害はいまだ報告されていない。著者らは最近，黄色鉛筆（ベンジジンイエローを含む）によつて眼瞼肉芽腫を形成した1例を経験し，さらに動物実験によりマウスの皮下に同様な腫瘤形成を認めたので報告する。

1) A 2-year-old boy got wounded at the upper lid by a yellow pencil with benzidine yellow, which resulted in a lid tumor. The tumor was extracted, which was histologically a granuloma consisting of fibrocytes, fibroblasts.reticulum cells, giant cells, lymphocytes, neu-trophil leucocytes, eosinophil leucocytes, and phagocytic cells with yellow pigment around the necrotic tissue.

2) Mice were inoculated at their upper lid and back with yellow, red, blue, pink, brown and white colored pencils and an ordinary black pencil. A week after the inoculation each of the colored pencils induced a tumor at the subcutaneous tissue.