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Japanese

Clinical Effect of VB12 Cobamamide on Retinitis Pigmentosa Koji Miyaura 1 , Masaru Kozaki 2 , Hisako Iwai 2 , Toshiaki Oura 3 , Gen Isshiki 3 , Isamu Uemura 4 , Kazuo Matsushita , Yoshiko Tani 1Ophthalmological Department of Osaka Medical College 2Department of Ophthalmology, Chidren's Medical Center of Osaka City 3The First Division, Department of Pediatrics, Chidren's Medical Center of Osaka City 4Department of Clinical Pathology, Chidren's Medical Center of Osaka City pp.31-37
Published Date 1970/1/15
DOI https://doi.org/10.11477/mf.1410204203
  • Abstract
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To decide whether a medicament is used for retinitis pigmentosa of the human or not, the most reasonable is to investigate the influence of the medicament on experimental retinitis pigmentosa of animal induced by NalO3 and the regeneration of visual purple of animal. Our previous observations clearly demonstrate that vitamin B12 (Cobamamide) prevent the evolu-tion of experimental retinitis pigmentosa of rats according to ERG and augment the regene-ration of visual purple of frogs according to Kimura's method.

Cobamamide has been administered to 20 cases of retinitis pigmentosa.


Copyright © 1970, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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