網膜色素変性の暗順応検査と周辺部残存視野

Peripheral visual field in patients of retinitis pigmentosa with fair dark adaptation

要約　目的：暗順応が良好な網膜色素変性患者での視野を含む視機能の報告。対象：網膜色素変性の患者4例8眼を対象とした。すべて女性で，初診時年齢は15歳，34歳，44歳，66歳であり，それぞれ12年，4年，12年，6年にわたり経過を追った。初診時の視力は0.8～1.2の範囲にあった。視野はGoldmann視野計，暗順応はGoldmann-Weekers暗順応計で検査した。全症例でのsingle flash electroretinogramはsubnormalであり，暗順応検査の結果は正常とされる10²～2×10³の範囲にあった。結果：全症例で固視点から10°以内の中心視野が維持され，これより外方に島状の暗点があり，加齢に伴い周辺視野の欠損が進む傾向があった。結論：暗順応が良い網膜色素変性では，中心視野が保存され，経過が良好な症例がある。

Abstract.　Purpose：To report the visual function including visual field in patients of retinitis pigmentosa with fair dark adaptation. Cases and Method：This study was made on 8 eyes of 4 patients of retinitis pigmentosa. All were females and were aged 15, 34, 44 and 66 years at their first visit. They were followed up for 12, 4, 12 and 6 years respectively. Visual acuity ranged from 0.8 to 1.2 initially. Visual field was evaluated by Goldmann perimeter. When tested by Goldmann-Weekers adaptometer, dark adaptation was fairly normal between 10² and 2×10³ in all the eyes. All the eyes showed subnormal responses for single flash ERG. Results：Central visual field was maintained within 10 degrees from the point of fixation in all the eyes throughout the course of observation. Island-shaped scotomas were present in the paracentral or peripheral visual field. Conclusion：Cases of retinitis pigmentosa are present that manifest fair dark adaptation with well-retained central visual field.