脈絡膜血管腫に対してベバシズマブ硝子体内注射が奏効した2例

Intraviteal injection of bevacizumab was effective in two cases of choroidal hemangioma

要約　目的：滲出性網膜剝離を伴う脈絡膜血管腫に対し，ベバシズマブ硝子体注射が奏効した2症例の報告。症例：1例は50歳女性，ほかの1例は46歳男性で，いずれも片眼性であり，それぞれ変視症と視力低下が主訴であった。蛍光眼底造影で脈絡膜血管と滲出性網膜剝離と診断された。罹患眼の視力はそれぞれ1.0と0.8であった。1例にはベバシズマブ硝子体内注射，ほかの1例には光線力学療法の10か月後にベバシズマブ硝子体注射を3回行った。滲出性網膜剝離は，1例では3か月後に消失し，ほかの1例では4か月後まで残存した。結論：滲出性網膜剝離を伴う脈絡膜血管腫に対し，ベバシズマブ硝子体注射が奏効することがある。

Abstract.　Purpose：To report 2 cases of choroidal hemangioma associated with exudative retinal detachment treated by intravitreal injection of bevacizumab. Cases：The present series comprised a 50-year-old female and a 46-year-old male. Both were unilaterally affected. Metamorphopsia and blurring of vision were chief complaints. Fluorescein angiograpy led to the diagnosis of choroidal hemangioma with exudative retinal detachment. Initial visual acuity in the affected eye was 1.0 and 0.8 respectively. One case received intravitreal injection of bevacizumab. The other case received photodynamic therapy followed by 3 sessions of intravitreal bevacizumab 10 months later. Exudative retinal detachment disappeared 3 months later in one case and persisted for 4 months in the other. Conclusion：These cases illustrate that intravitreal bevacizumab may be effective for exudative retinal detachment secondary to choroial hemangioma.