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Review of diagnosis and clinical course of retinoblastoma Mayo Nozaki 1,2 , Satoru Kase 2 , Kazuhiko Yoshida 2 , Kan Ishijima 3 , Mika Noda 2 , Shigenobu Suzuki 4 , Noriyuki Azuma 5 , Susumu Ishida 2 1Dept of Ophthalmol,Obihiro Kyokai Hosp 2Dept of Ophthalmol,Hokkaido Univ Grad Sch of Med 3Dept of Ophthalmol,Hokkaido Tokeidaikinen Hosp 4Dept of Ophthalmic Oncol,Nat Cancer Cent Hosp 5Dept of Ophthalmol,Nat Cent for Child and Development pp.1123-1127
Published Date 2011/7/15
DOI https://doi.org/10.11477/mf.1410103754
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Abstract. Purpose:To report 7 cases of retinoblastoma regarding initial diagnosis and clinical course. Cases:A retrospective study was made on 7 cases seen during the past 8 years. Results:The series comprised 2 boys and 5 girls. Five cases were unilaterally and two were bilaterally affected. Six cases were younger than 4 years and one was 7 years at the initial diagnosis. Chief complaints comprised leukocoria and squint in 5 cases,impaired vision in one,and hyperemia with edema of eyelid in one. Retinoblastoma was classified from stage B to E. Three eyes were in stage E at the time of diagnosis. Enucleation was performed in 5 eyes and orbital exenteration in one as the initial treatment. Enucleation became necessary in 2 out of 3 eyes that were conservatively treated. There was no metastasis in 6 eyes that received enucleation or exenteration. Two cases that developed extraocular infiltration resulted in fetal outcome. Initial clinical features in these 2 cases did not match with the final outcome. Conclusion:Clinical features of retinoblastoma at the initial diagnosis are not indicative of prognosis.


Copyright © 2011, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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