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要約 目的:網膜静脈閉塞症に続発した黄斑浮腫に対して酢酸メチルプレドニゾロンを後部テノン囊下に注射した効果の報告。対象と方法:黄斑浮腫が続発し,3か月以上寛解しない網膜中心静脈閉塞症2眼と網膜静脈分枝閉塞症3眼を対象とした。酢酸メチルプレドニゾロン10mgを後部テノン囊下に注射し,3か月間の経過を追跡した。視力はlogMARで評価した。結果:注射後3か月で視力は2眼で改善し,3眼では不変であった。平均視力は3か月後に有意に改善した。光干渉断層計(OCT)で測定した中心窩厚と黄斑浮腫には変化がなかった。副作用はなかった。結論:黄斑浮腫がある網膜中心静脈閉塞症または網膜静脈分枝閉塞症に対し,酢酸メチルプレドニゾロン10mgのテノン囊下注射は安全ではあるが,黄斑浮腫の改善効果は少ない。
Abstract. Purpose:To report the outcome of subtenon injection of methylprednisolone acetate for retinal vein occlusions. Cases and Method:This study was made on 5 eyes of 5 patients with macular edema. Central retinal vein occlusion(CRVO)was present in 2 eyes and branch retinal vein occlusion(BRVO)in 3 eyes. Macular edema showed no tendency to spontaneous resolution during the foregoing 3 months. Each eye received posterior subtenon injection of 10 mg methylprednisolone acetate and was followed up for 3 months or longer. Visual acuity was evaluated in terms of logMAR. Results:Visual acuity improved in 2 eyes and remained unchanged in 3 eyes after 3 months of injection. Averaged visual acuity significantly improved after 3 months. There was no change in macular edema or retinal thickness in the fovea as measured by optical coherence tomography(OCT). There was no complication throughout the course of observation. Conclusion:Posterior subtenon injection of 10 mg methylprednisolone acetate was safe but failed to show marked improvement in macular edema in eyes with CRVO or BRVO.
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