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A case of Vogt-Koyanagi-Harada disease with recurrence twenty-one years later Misuzu Kondo 1 , Asami Nakahira 1 , Toshiaki Nakakuki 1 , Eriko Matsushita 1 , Koji Nishino 1 , Atsuki Fukushima 1 1Dept of Ophthalmol,Kochi Med Sch pp.1641-1645
Published Date 2009/10/15
DOI https://doi.org/10.11477/mf.1410102897
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Abstract. Purpose:To report a case of Vogt-Koyanagi-Harada(VKH)disease that recurred 21 years later. Case:A 33-year-old female visited us for metamorphopsia and blurring since 7 days before. Her corrected visual acuity was 0.1 right and 0.4 left. Both eyes showed multiple serous retinal detachment in the macular area. Cerebrospinal fluid showed no pleocytosis. She was diagnosed with posterior-type VKH disease. Treatment with intravenous prednisolone at the daily dosis of 200 mg was followed by disappearance of retinal detachment. Recurrence:The patient noticed blurring in her right eye at the age of 54 years,or 21 years after the episode. When seen 7 days later,her corrected visual acuity was 0.6 right and 1.0 left. The right eye showed ciliary injection,cells in the aqueous,and Koeppe nodules on the iris as typical signs of granulomatous anterior uveitis. Both eyes showed sunset-glow fundus without retinal detachment or disc hyperemia. She was diagnosed with unilateral VKH disease. Treatment with topical corticosteroid was followed by cure of uveitis in the right eye. She has been doing well for 5 months until present. Conclusion:This case illustrates that VKH disease may recur after a long interval. This case is characterized by bilateral posterior uveitis during the initial episode and by unilateral anterior uveitis at the recurrence.


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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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