Rinsho Ganka Volume 61, Issue 4 (April 2007)

Decrease of central scotoma in a case of Leber optic neuropathy after peroral lutein supplement Ryoko Oki 1 , Junko Ikewaki 1 , Celso S Matsumoto 1 , Masamoto Imaizumi 1 , Kazuo Nakatsuka 1 1Dept of Ophthalmol, Oita Univ Sch of Med pp.575-579
Published Date 2007/4/15
DOI https://doi.org/10.11477/mf.1410101738
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Abstract. Purpose:To report a case of Leber optic neuropathy that improved after peroral lutein supplement. Case:A 26-year-old female had noted bilateral blurring of vision at the age of 19 years. Detection of 14484 mutation led to the diagnosis of Leber optic neuropathy. Clinical Course:Her corrected visual acuity decreased to 0.02 in either eye one year after diagnosis. Since 20 months before, she started self-medication of peroral supplement that contains high dosis of lutein. She noted improved visual functions after 2 months of medication. Her corrected visual acuity improved to 0.03 right and 0.4 left. Islands of improved sensitivity appeared within the central scotoma by program 10-2 of Humphrey perimetry. Conclusion:Anti-oxidative material in lutein supplement may improve visual function in Leber optic neuropathy.

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61巻4号 (2007年4月)
電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院