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要約 目的:慢性緑内障に投与されている治療薬の実態報告。対象:2003年5月に岐阜大学医学部附属病院眼科緑内障専門外来を受診した慢性緑内障265例265眼を対象にした。男性131例,女性134例で,年齢は26~90歳(平均62歳)である。病型は,正常眼圧緑内障148例,原発開放隅角緑内障98例,落屑緑内障19例である。結果:使用薬剤は,プロスタグランジン製剤230例,β遮断薬155例,炭酸脱水酵素阻害薬74例,α遮断薬27例,交感神経刺激薬22例,副交感神経刺激薬20例であった。使用薬物数は,1剤103例(39%),2剤87例(33%),3剤53例(20%),4剤18例(7%),5剤4例(1.5%)であった。結論:ラタノプロストとβ遮断薬の使用頻度が高く,薬物数は3剤までが多かった。
Abstract. Purpose:To report the current status of medication prescribed to glaucoma patients. Object and Method:This retrospective study was made on 265 eyes of 265 patients who visited glaucoma clinic of Gifu University Hospital during May 2003. The series comprised 131 males and 134 females. The ages ranged from 26 to 90 years,average 62 years. There were normal-tension glaucoma 148 cases,primary open-angle glaucoma 98 eyes,and capsular glaucoma 19 cases. Results:The prescribed medication comprised prostaglandin-related compounds 230 cases,beta-blockers 155 cases,carbonic anhydrase inhibitors 74 cases,alpha-blockers 27 cases,symphathomimetics 22 cases,and parasympathomimetics or miotics 20 cases. One drug alone was prescribed in 103 cases(39%),two in 87 cases(33%),three in 53 cases(20%),four in 18 cases(7%),and five in 4 cases(1.5%). Conclusion:Latanoprost and beta-blockers were most frequently prescribed medications for chronic glaucoma. Majority of patients were receiving three or less medications.
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