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Mazabraud Syndrome of the Right Leg. Case Report Tetsuo SHIMOYAMA 1 , Mitsuru TAKAHASHI 1 , Hirohisa KATAGIRI 1 , Hideki MURATA 1 , Junji WASA 1 , Takayoshi SUZUKI 1 1Department of Orthopaedic Surgery, Shizuoka Cancer Center Keyword: 線維性骨異形成 , fibrous dysplasia , 筋肉内粘液腫 , intramuscular myxoma , 悪性転化 , malignant transformation pp.389-393
Published Date 2012/4/25
DOI https://doi.org/10.11477/mf.1408102326
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 We report the case of a 65-year-old woman with Mazabraud syndrome. The patient presented with a mass in the right leg during treatment for lung cancer, and radiography revealed an osseous lesion of her right fibula. The mass was diagnosed as an intramuscular myxoma by histological examination of an open biopsy specimen, and the osseous lesion was diagnosed as fibrous dysplasia based on the X-ray findings. Sarcomatous change, has been reported to occur in only 0.5% of patients with solitary fibrous dysplasia, whereas malignant change has been reported to occur in as high as 8.3% of patients with Mazabraud syndrome. Consequently, patients with Mazabraud syndrome should be closely followed-up for evidence of malignant transformation.


Copyright © 2012, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1286 印刷版ISSN 0557-0433 医学書院

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