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Primary Leiomyosarcoma of Bone. Case Report Gentaro Kinoshita 1 , Hitoshi Yasoshima 3 , Takahito Shiraki 1 , Yutaka Kominato 1 , Satoshi Nagareda 2 1Department of Orthopaedic Surgery, Takarazuka Municipal Hospital 2Department of Pathology, Takarazuka Municipal Hospital 3Clinical Inspection Center, Yao General Hospital Keyword: leiomyosarcoma , 平滑筋肉腫 , primary bone tumor , 骨原発 , metastatic cancer , 骨転移癌 pp.197-201
Published Date 2006/2/1
DOI https://doi.org/10.11477/mf.1408100261
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 A case of primary leiomyosarcoma of the proximal tibia is reported. No abnormal findings were detected in the blood examination, including tumor marker levels. A plain radiograph, MRI scan, and bone scintigrams revealed non-specific evidence of malignancy in the left proximal tibia. Microscopic examination showed spindle cell sarcoma with positive staining for smooth muscle actin, and the histological diagnosis was leiomyosarcoma. The tumor was widely resected, and reconstruction was with an HMRS tumor prosthesis. The extensor mechanism of the knee joint was covered with reversed gastrocnemius and reserved patella tendon. No evidence of recurrence or metastasis has been detected one year after the operation. Primary leiomyosarcoma is uncommon, and must be differentiated from its counterpart of soft tissue origin and from metastases from internal organs, such as the uterus and the intestine.


Copyright © 2006, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1286 印刷版ISSN 0557-0433 医学書院

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