Radiation Induced Glioblastoma:A case report Naoki Kato 1 , Takamasa Kayama 1 , Kaori Sakurada 1 , Makoto Saino 1 , Akira Kuroki 1 1Department of Neurosurgery, Yamagata University School of Medicine Keyword: radiation induced glioma , MIB−1 , glioblastoma , radiation necrosis , pituitary adenoma pp.413-418
Published Date 2000/5/1
DOI https://doi.org/10.11477/mf.1406901597
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We report a surgical case of a 54-year-old woman with a radiation induced glioblastoma. At the age of 34, the patient was diagnosed to have a non-function-ing pituitary adenoma. It was partially removed fol-lowed by 50 Gy focal irradiation with a 5×5 cm lateral opposed field. Twenty years later, she suffered from rapidly increasing symptoms such as aphasia and right hemiparesis. MRI showed a large mass lesion in the left temporal lobe as well as small mass lesions in the brain stem and the right medial temporal lobe. These lesions situated within the irradiated field.

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