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Diagnostic Criteria of Neurosarcoidosis Manabu Sakuta 1 , Toshihide Kumamoto 2 , Takahiro Iizuka 3 , Kazutoshi Nishiyama 1 , Masaru Oritsu 4 1Department of Neurology, Kyorin University Medical School 2Department of Neurology, Ooita University 3Department of Neurology, Kitasato University 4Department of Respiratory Medicine, Japanese Red Cross Medical Center Keyword: neurosarcoidosis , CNS sarcoidosis , sarcoid neuropathy , sarcoid myopathy , sarcoidosis pp.471-476
Published Date 2006/6/1
DOI https://doi.org/10.11477/mf.1406100378
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 We have collaborated with Japanese Sarcoidosis Society and Japanese Society of Respiratory Disease to provide a new diagnostic criteria of neurosarcoidosis.

 At least two of six examinations are important. These include bilateral hilar lymphadenopathy, abnormal uptake of 67Ga scintigraphy, broncho alveolar lavage fluid examination, elevated serum ACE, negative tuberculin reaction, and elevated serum or urinary calcium level.(definite)Having positive clinical findings which suggest a neurosarcoidosis. Pathology proven case.(probable)Having positive clinical findings which suggest a neurosarcoidosis. Pathology proven in other organ. At least two of six examinations are positive.(possible) Having positive clinical findings which suggest a neurosarcoidosis. At least two of six examinations are positive.

 CNS sarcoidosis, sarcoid neuronopathy and sarcoid myopathy are separately diagnosed. Kveim reaction which is time consuming, not so specific, and difficult to obtain its antigen is no more necessary.


Copyright © 2006, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 2185-405X 印刷版ISSN 0006-8969 医学書院

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